-1.7 C
London
Friday, January 10, 2025
HomeNewsPotential approach to stop growth of brain cancer cells

Potential approach to stop growth of brain cancer cells

Related stories

J&K police release list of seized assets used for terrorism

Jammu, Feb 16 : The police in Jammu and...

Israel says 4 mln citizens vaccinated against Covid-19

Jerusalem, Feb 17 : Israeli officials announced that some...

Hungary to receive first shipment of Chinese vaccines

Beijing, Feb 17 : A Hungarian cargo plane loaded...

Toronto, Feb 13 : Inhibiting a key enzyme that controls a large network of proteins important in cell division and growth leads the way for a new class of drugs that could stop a deadly brain cancer from growing, a new study suggests.
The study, published in the journal Nature Communications, showed that chemically inhibiting the enzyme PRMT5 can suppress the growth of glioblastoma cells.
The inhibition of PRMT5 led to cell senescence, similar to what happens to cells during ageing when cells lose the ability to divide and grow. Cellular senescence can also be a powerful tumour suppression mechanism, stopping the unrelenting division of cancer cells.
“By inhibiting one protein, PRMT5, we were able to affect a cascade of proteins involved in cell division and growth,” said researcher Cheryl Arrowsmith from the University of Toronto.
“The traditional way of stopping cell division has been to block one protein. This gives us a new premise for the future development of novel, more precise therapies,” Arrowsmith added.
For the study, the team tested a group of new experimental small molecules designed to specifically inhibit key cellular enzymes being developed and studied to see if any would stop the growth of glioblastoma brain tumour cells in the laboratory.

Subscribe

- Never miss a story with notifications

- Gain full access to our premium content

- Browse free from up to 5 devices at once

Latest stories